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Microdosingessentially, taking a smaller dose of something than is normally prescribedhas taken off among some users of GLP-1 medications, including semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro)

In this narrative literature review, we explore the pharmacological properties of tirzepatide and critically summarize and comment on the results of the clinical studies conducted thus far, as well as discuss the potential implications for the treatment of obesity, T2DM, and associated cardiometabolic complications

For a deeper look at vascular and cardiometabolic risk, see our pages on Preventive Cardiology and Silent Heart Disease Detection, Metabolic Health and Longevity Medicine, and ApoB and Longevity

Research suggests low-carbohydrate diets may help improve insulin sensitivity and reduce blood glucose levels in some individuals, especially those with obesity or type 2 diabetes