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Antioxid Redox Signal 16(10):11091118

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Key Takeaways Sermorelin is a 29-amino-acid GHRH analogue with a plasma half-life of roughly 10-20 minutes, preserving natural GH pulsatility in a way longer-acting analogues do not

It has Phase 3 REDEFINE-1 data showing about 22.7% weight loss at 68 weeks, and an NDA was filed with FDA in December 2025