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p = 0.006) over a mean follow-up of 47.5 10.9 months (Table 1)

During shortages of Wegovy, Ozempic, Mounjaro, and Zepbound, the FDA exercised temporary enforcement discretion , allowing compounding pharmacies to help meet patient demand. Once manufacturing stabilized: Semaglutide injection products were removed from the FDA Drug Shortage List Tirzepatide injection products were formally declared resolved Compounding reverted to pre-shortage federal and state limits Broad, shortage-based compounding is no longer allowed in 2026

Second, GLP-1 RAs can reduce inflammation in coronary arteries

Tech transfer requires cross-validation of HPLC/LC-MS methods so impurities and host-cell proteins are measured the same way in both sites