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Bogaards JJP, Venekamp JC, Van Bladeren PJ (1997) Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the and P1-1

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3.2.3 Treatment of pulmonary diseases Idiopathic pulmonary fibrosis is a chronic and progressive interstitial lung disease characterized by excessive fibrosis of the lung tissue and is associated with high morbidity and mortality rates ( ERCs also exhibit multipotent therapeutic potential in Idiopathic pulmonary fibrosis treatment (Zhao et al., 2018a)

These transmembrane enzymes utilize NADPH to reduce O 2 , directly producing H 2 O 2 (as by NOX4, DUOX1/2) [72] or indirectly via O 2 generation (by NOX1-3) [73], which rapidly dismutates to H 2 O 2