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Individuals who have had mold exposure (asthma is a red flag for this), or who have been exposed to excess chemicals (such as hairdressers, construction workers, and many other professionals), can be at risk for a liver backlog

Histological evaluation of major organs and blood tests reveal no signs of systemic toxicity or inflammatory pathology, supporting a favorable safety profile

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Pre-existing gastrointestinal conditions, particularly gastroparesis or irritable bowel syndrome, significantly affect tolerability and may necessitate slower escalation or lower maintenance doses