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Patients received flexible doses of oral semaglutide (up to 14 mg) or placebo over 156 weeks alongside standard care

Retatrutides triple mechanism is why it produces 24.2% average weight loss compared to 20.9% for Tirzepatide (dual agonist) and 14.9% for Semaglutide (single agonist)

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While generally safe, certain individuals should consult a healthcare professional before starting: Pregnant or breastfeeding women People with chronic medical conditions Individuals on long-term medication Those with known allergies to marine sources This is a precaution, not a warning informed use is always the safest approach