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Thus, it is important to ensure efficient levels of B12 are maintained within the body as women get older

Examples include OATD-02, a recently developed ARG1/2 dual inhibitor with 15 nM affinity (Borek et al., 2023) and CB-1158, which has IC 50 values of 86 nM and 296 nM for ARG1 and ARG2, respectively (Naing et al., 2024

Perhaps, the simultaneous use of therapies founded on lipid peroxidation along with remedies that either inhibit antioxidant mechanisms, or adversely interact with other pathways, may help bypass this problem [283]