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This cyclical structure is what makes it sustainable as a long-term longevity tool

Because no studies have been done on the effect of using ALA supplements during pregnancy, don't use it if you're pregnant

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Studies have suggested that other ion channels, such as histamine-gated chloride channels, pH-gated chloride channels, nicotinic acetylcholine receptors (nAChRs), and gamma amino butyric acid (GABA)-gated chloride channels are also targeted, but this may be a downstream effect as a result of glutamate-gated chloride (GluCl) channel inhibition (Fuse et al