They play a critical role in regulating numerous biological functions, including hormone balance, immune response, inflammation control, cognitive performance, and tissue repair
Genetic evidence, such as GWAS, has identified the single-nucleotide polymorphism (SNP) in GIPR, showing that lower function of GIPR is associated with lower BMI (6466), allowing speculation that higher GIPR activity is obesity promoting
Compounding the issue is that more intense or longer exercise sessions can also cause you to lose even more of these electrolytes, especially if performed at higher temperatures
A few studies suggested that stopping GLP-1s is associated with regaining at least a portion of the lost weight, but its possible that if you go slowly, you may be more likely to keep the weight off