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doi: 10.2147/DDDT.S79458 198 HunterDJBierma-ZeinstraS

In NASH patients ( n = 10), oxidative DNA damage was significantly increased compared to healthy controls ( n = 16) despite similar rates of FAO following an intravenous infusion of lipids, suggesting increased susceptibility to oxidative stress in these patients [89]

doi:10.1136/svn-2018-000143 Spence JD, Hankey GJ

Muscle-specific insulin resistance by the muscle-specific deletion of IRTK or GLUT4 increased the susceptibility to hepatic steatosis, and increase adiposity in animal models [29,30]