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The injection of lentivirus carrying sh-lncRNA XIST plasmids reduces levels of TNF-, IL-2, and IL-6 to suppress inflammatory and damage in cartilage tissues (270)

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Ligand-receptor analysis deciphers the crosstalk driving inflammation: injured proximal tubular cells adopt a pro-inflammatory phenotype and upregulate chemokines, while fibroblasts significantly overexpress ligands like CCL2 , CCL19 , and CCL21 to recruit immune cells via receptors such as CCR2 and CCR7 (Liu et al., 2025)

All authors have reviewed the final version of the manuscript and approved it for publication